Technology Services

IBPR-IBPR offers platform technology services of pharmacology, pharmacokinetics, exploratory toxicology, metabolite target analysis and physicochemical characterization for the discovery of small molecule drugs.

Customized services needed for lead compound and drug candidate selections are available upon inquiry.

Technology Services：

Efficacy Evaluation In Disease Animal Models
Service number	Technology and Service List
BP-AM-001	Subcutaneously xenografted tumor growth models-mouse
BP-AM-002	Orthotropically xenografted tumor growth models-mouse
BP-AM-003	STZ-induced diabetic model-rat
BP-AM-004	Diet-induced obese mouse model
BP-AM-005	Oral glucose tolerance test-mouse
BP-AM-006	Oral glucose tolerance test-rat
BP-AM-007	IVIS Spectrum 3D image-mouse

Pharmacokinetics and Metabolite Target Analysis
Service number	Technology and Service List
BP-PK-001	Analytical method development
BP-PK-002	Bioanalytical method development
BP-PK-003	Protein binding determination
BP-PK-004	Microsomal stability evaluation
BP-PK-005	CYP inhibition assay
BP-PK-006	PK/bioavailability in mice
BP-PK-007	PK/bioavailability in rats
BP-PK-008	PK/bioavailability in minipigs
BP-PK-009	Metabolite identification

Physicochemical Characterization
Service number	Technology and Service List
BP-PD-001	X-ray Powder Diffraction (XRPD)
BP-PD-002	Raman Spectroscopy
BP-PD-003	Dynamic Vapor Sorption (DVS)
BP-PD-004	Water content (Karl Fischer coulometric titrator)
BP-PD-005	Differential scanning calorimetry (DSC)
BP-PD-006	Thermogravimetric analyzer (TGA)
BP-PD-007	Capsule filling and sealing systems
BP-PD-008	Dissolution tests
BP-PD-009	Micro-Osmometer
BP-PD-0010	Air jet mill micronizer

Chemical Characterization
Service number	Technology and Service List
BP-CH-001	Nuclear Magnetic Resonance Spectroscopy (NMR)
BP-CH-002	Liquid Chromatography / Mass Spectroscopy (LC/MS)
BP-CH-003	Purity Check (Purity)

In Vitro Toxicity
Service number	Technology and Service List
BP-IVT-001	MTS assay
BP-IVT-002	In vitro hemolysis assays ( mouse, rat, rabbit, dog, pig, and minipigs)

Antibody aggregation analysis and Antibody humanization
Service number	Technology and Service List
BP-CM-001	Antibody humanization design
BP-CM-002	Antibody aggregation analysis and modification

Human coronavirus test
Service number	Technology and Service List
BP-HCoV-001	Inhibition test for Human coronavirus HCoV-OC43
BP-HCoV-002	In vitro FRET based SARS-CoV-2 3CL protease assay

Cell and enzyme-based screening platform
Service number	Technology and Service List
BP-CE-001	The cell-based screening platform of NRF2 modulators (cancer prevention or therapy)
BP-CE-002	The cell-based screening platform of NRF2 activators (neuroprotection)
BP-CE-003	The enzyme-based screening platform of MTHFD1 inhibitors
BP-CE-004	The enzyme-based screening platform of MTHFD2 inhibitors

3D tissue image analysis
Service number	Technology and Service List
JB-001	3D Fluorescence Imaging and Metrological Analysis of Animal Tissue(including Spheroid Organoid) Samples

Service charges may be subject to the condition of the studies requested. Please feel free to contact us via bp-service@nhri.edu.tw for the cases of your interest.

IBPR-Service Request Form Download: WORD PDF

Please complete the IBPR-Service Request Form and email bp-service@nhri.edu.tw to us.

If you are interested in our services of compound synthesis, please refer to https://ibpr.nhri.org.tw/en/index.php/vmic/