VMIC

VMIC

AIM

To elaborate the well-established technologies and experiences in innovative drug discovery, and to fit in the vision of government for establishing Taiwan as an Asia-Pacific Biopharmaceutical R&D Industrial Center (亞太生技醫藥研發產業中心), IBPR actively participates in the program organized by the Academia Sinica for Translational Innovation of Biopharmaceutical Development, Technology Supporting Platform Axis Scheme. Under this program, IBPR starts up a new platform called Value-Added MedChem Innovation Center (VMIC) from 2017 to leverage integrated medicinal chemistry research with well-established drug research platform technologies to support the small molecule drug discovery projects for the companies stationed in the National Biotechnology Research Park and academic/research institutes. VMIC’s mission is to provide customer-driven service or collaboration in medicinal chemistry for hit-to-lead and lead-to-candidate. IBPR also exerts its systematic research mechanism and experiences in drug discovery and development stages to bridge the long-existing gap between academia research and industrialization. VMIC’s goal is to enable local pharmaceutical and biotech companies to engage in innovative drug discovery and to upgrade the entirety of the biotechnology and pharmaceutical industry in Taiwan.

WHAT WE DO

  • Hit-to-lead optimization
  • Lead-to-candidate optimization
  • Library synthesis
  • Process development and scale-up
  • Custom synthesis service
  • Analytical method development

SERVICE MODE

FTE Program (chemistry only)

  • No biological data sharing
  • No compound design involved
  • MedChem lab help the synthetic method development for novel compounds

FTE Program (medicinal chemistry included)

  • Biological data sharing
  • Compound design involved
  • Computer aided drug design
  • MedChem lab help the synthetic method development for novel compounds

FFS Program

  • Library synthesis
  • Process development and scale-up
  • Custom synthesis (gram scale compounds, competitive compounds, RS)
  • Analytical method development

CORE EQUIPMENT

NMR (Varian)
Agilent 400 MHz & 300 MHz
NMR-2NMR-1
UPLC & H-Class Waters
UPLC-H1UPLC-H2
Analytical HPLC
Hitachi L2100 Series
HPLC
LC/MSD Waters
LCMSD-waters
LC/MSD Agilent (1100 & 1200)
LCMSD-agilent
Microwave CEM
Microwave-CEM
CombiFlash®Rf
CombiFlash
Chemical Inventory (over 7,000)
Chemical Inventory

CONTACT US

Ms. Pei-Hsien Pan

Tel: (037)206166 ext. 35742/35744

Mail: VMIC@nhri.edu.tw

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